Contents: Proteomics 16'23

Pharmaceutical Advances and Proteomics Researches

Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...

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CONTENTS Contents �

We illustrate the use of functional system speci cations and their re nement in the development of system components by a simple case study The development includes the modular speci cation re nement and veri cation of system components We start the development with an informal description of the tasks of the case study and then step by step carry out the tasks formally The informal requirement...

Pharmaceutical Advances and Proteomics Researches

Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...

Biol. Pharm. Bull. 30(9) 1617—1623 (2007)

The innate immune system is the first line of host defense against infectious microbes. Toll-like receptors (TLRs) are a family of receptors that trigger innate immune reactions in response to various microbial products, such as lipopolysaccharide (LPS), flagellin, double-stranded RNA, CpG-DNA, and others. Stimulation of TLRs leads to the activation and maturation of antigen-presenting cells, s...